Author Archives: azaleaazelia

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COVID-19 vaccine development part 8

Immunogens used to develop viral vaccines Peptides : Synthetic produced fragment of an antigen Rapid development Poorly immunogenic; high cost Example of vaccines : COVID-19 vaccines in development

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COVID-19 vaccine development part 7

Immunogens used to develop viral vaccines : Recombinant : Host cell is used to express an antigen No need to produce the whole virus May be  poorly immunogenic; high cost Example of vaccines : Hepatitis B

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COVID-19 vaccine development part 6

Immunogens used to develop viral vaccines: Protein subunit:  A protein derived from a pathogen May have fever side effects than whole virus (redness, swelling at injection site) May be poorly immunogenic, complex process Example of vaccine : Influenza

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COVID-19 vaccine development part 5

Immunogens used to develop viral vaccines: Whole inactivated virus: Inactivated dead virus Induces strong antibody response Requires large quantities of virus Influenza, rabies, hepatitis A

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COVID-19 vaccine development part 4

Immunogens used to develop viral vaccines Attennuated live virus: Live virus but doesn’t cause disease Induces same response as natural infection Not recommended  for pregnant women and immunocompromised persons Measles,  rubella, mumps, yellow fever, smallpox (Vaccinia)

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COVID-19 vaccine development part 3

 How vaccines are delivered? A vaccine can be administered through different routes, for example injection in the muscle or under skin or via the oral route Vaccines sometimes require more than one dose to: build complete immunity give a “booster” … Continue reading

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COVID-19 vaccine development part 2

How vaccines work? Vaccines greatlynreduce the risk of infection by training the immune system to recognize and fight pathogens such as viruses or bacteria. Vaccines safely deliver an immunogen which is a specific type of antigen that elicits an immune … Continue reading

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COVID-19 vaccine development part 1

Why we use vaccines? Vaccines can prevent infectious disease. Examples of vaccine-preventable disease are: measles, polio, hepatitis B, influenza and many others. When most people in a community are vaccinated against a disease, the ability of the pathogen to spread … Continue reading

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Imaging in coronavirus disease 2019 part 4

The virus outbreak presumably originated via a zoonotic transmission linked to the seafood market in Wuhan (China) and later accelarated with human to human transmission, causing the severe subsequent outbreak. Since the original outbreak, SARS-CoV2 has rapidly spread across the … Continue reading

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Imaging in coronavirus disease 2019 part 3

In late November 2019, a serious form of pulmonary illness originated in Wuhan City (Hubei province, China) an engulfed a majority of the world. This pneumonia outbreak was attributed to a novel coronavirus, a lipid-enveloped RNA virus, which was named … Continue reading

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