Author Archives: azaleaazelia

Subunit vaccines Immune response: Subunit vaccines, like inactivated whole-cell vaccines do not contain live components of the pathogen. They differ from inactivated whole-cell vaccines, by containing only the antigenic parts of the pathogen. These parts are necessary to elicit a … Continue reading →

Inactivated whole-cell vaccines Safety and stability: Inactivated whole-cell vaccine have no risk of inducing the disease they are given against as they do not contain live components They are considered more stable than LAV vaccines.

Inactivated whole-cell vaccinations Immune response: Inactivated-whole cell vaccines may not always induce an immune response and the response may not be long lived Several doses of inactivated whole-cell vaccines may be required to evoke a sufficient immune response

Inactivated whole-cell vaccinations Inactivated vaccines are made from microorganism (viruses, bacteria, other) that have been killed through physical or chemical process. These killed organisms cannot cause disease.

Yellow fever (YF): Hypersensitivity reactions Very rare Sensitivity to egg, which is commonly used to stabilize the vaccine, may explain at least some of these cases 2. Vaccine-associated neurotropic disease (encephalitis) Very rare Infants seem more susceptible to vaccine-associated neurotropic … Continue reading →

Rotavirus: None reported to WHO To date, post-licensure surveilance does not indicate any increased risk of intussuception or other serious adverse reaction associated with the use of current rotavirus vaccines

Measles: Febrile seizure  uncommon at 0.3% Adverse reactions, with the exception of allergic anaphylactic reactions, are less likely to occur after receipt of the second dose of measles vaccine 2. Thrombocytopenic purpura Very rare at 0.03% Adverse reactions, with the … Continue reading →

Oral Polio vaccine (OPV): Vaccine-associated paralytic poliomyelitis (VAPP) in vacciness and their contacts Very rare at 0.00002-0.0004% An essential component of the global polio eradication campaign despite adverse reactions

Tuberculosis (BCG): Fatal dissemination of BCG infection Very rare  at  0.000019-0.000159% Almost exclusively occurs in inadvertently immunized persons with severely compromised cellular immunity 2. BCG osteitis Very rare In the past BCG osteitis has been reported in connection with certain … Continue reading →

Five WHO recommended vaccines using LAV technology: Tuberculosis (BCG) Oral polio vaccine (OPV) Measles Rotavirus Yellow fever