Author Archives: azaleaazelia

Potential advantages of combination vaccines include: Reducing the cost of stocking and administering separate vaccines Reducing the cost of extra health care visits Improving timeliness  of vaccination (some parents and health-care providers object to administering more than two or three … Continue reading →

Combination vaccines Licensed combination vaccines undergo extensive testing before approval by national regulatory authorities to assure that the produce are safe, effective and of acceptable quality. Combination vaccines consist of two or more antigens in the same preparation. This approach … Continue reading →

Toxoid vaccines Immune response: May require several doses and usually need an adjuvant Not highly immunogenic Safety and stability: Vaccine cannot cause disease it prevents Very rare local and systemic reactions Usually stable and long lasting  

Toxoid vaccines Safety and stability Toxoid vaccines are safe because they cannot cause the disease they prevent and there is no possibility of reversion to virulence. The vaccine antigens are not actively multiplying and do not spread to unimmunized individuals. … Continue reading →

Toxoid vaccines Toxoid vaccines are based on the toxin produced by certain bacteria (e.g.tetanus or diptheria). The toxin invades the blood stream and is largely responsible for the symptoms of the disease. The protein-based toxin is rendered harmless (toxoid) and … Continue reading →

Adverse reactions associated with conjugate vaccines: Haemophilus influenzae type b conjugate None known Hib vaccine has not been associated with any rare more severe adverse reactions Pneumococcal conjugate None known PCV conjugate vaccines have not been associated with any rare, … Continue reading →

Conjugate subunit vaccines Conjugate subunit vaccines also create a response against the molecules in the pathogen’s capsule. In comparison to plain polysaccharide vaccines, they benefit from a technology that binds the polysaccharide to a carrier protein that can induce a … Continue reading →

Protein-based subunit vaccines More about Hepatitis B vaccines The first available hepatitis B vaccines were plasma-derived, produced by harvesting hepatitis B surface antigen (HBsAg) from the plasma of persons with chronic HBV infection. The particles are highly purified, and any … Continue reading →

Protein-based subunit vaccines More about Pertussis vaccine Both acellular (aP) and whole-cell pertussis (wP) vaccines are safe and effective. In terms of rare, more severe adverse reactions, aP and wP vaccines appear to have the same high level of safety. … Continue reading →