Types of vaccine part 45

Components of a vaccine

Preservatives

Thiomersal:

  • Very commonly used preservative. Thiomersal is an ethyl mercury-containing compound
  • It has been in use since the 1930ies and no harmful effects have been reported for doses used in vaccination except for minor reactions (e.g.redness, swelling at injection site)
  • It is used in multidose vials and for single dose vials in many countries as it helps reduce storage requirements/costs
  • Thiomersal has been subjected to intense scrutiny, as it contains ethyl mercury. The Global Advisory Committee on Vaccine safety continuosly review the safety aspects of Thiomersal. So far, there is no evidence of toxicity when exposed to Thiomersal in vaccines. Even trace amounts of thiomersal seem to have no impact on the neurological development of infants.

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