COVID-19 vaccine development part 14

Nucleic acid vaccines :

  • Instead of a virus, a protein antigen, or a virus expressing the protein, nucleic acid coding for the antigen is injected
  • DNA plasmid: enters nucleus, translated to mRNA for expression of protein
  • Or  mRNA can be injected. More direct (no translation required) but less stable than DNA
  • This is new technology – no other vaccines for human use have used this

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