Other most important research on plasma therapy is ongoing. Several convalescent patients are donating plasma against COVID-19 based on the positive results of another coronavirus. Surprisingly, it has preliminarily obtained favourable results in severe COVID-19 patients. On the other hand, the recombinant human monoclonal antibody is a straightforward path to neutralize viral load of COVID-19. CR3022 is a coronavirus-specific human monoclonal antibody that can bind to the receptor-binding domain of COVID-19, this has the potential to be developed as candidate therapeutics of COVID-19 disease. Other monoclonal, m396, CR3014 antibodies, neutralizing COVID-19 that may be an alternative for treatment of more severe cases.