Novel 2019 Coronavirus structure part 23

Recently, Jin et al., have constructed a homology model for COVID-19 main protein and they used molecular docking to monitor whether the N3 binds with it. The docking showed that N3 binds with the COVID-19 main protease. Subsequently, the crystal structure of COVID-19  main protease in complex with N3 inhibitor  have been determined at 2.3A resolution and deposited in the protein data bank, where the N3 inhibitor binds with the residues of 164-168 in the long strand 155-168 residues, and with residues 189-191 of the loop connecting between second and third region.

About azaleaazelia

A nice person... :)
Image | This entry was posted in Tak Berkategori. Bookmark the permalink.

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Google photo

You are commenting using your Google account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s