Continuous and discontinuous RNA synthesis in coronaviruses part 73

SUMMARY POINTS:

  • Coronavirus RNA synthesis is associated with extensive modification of intracellulr membranes, including DMVs and CMs
  • The requirement of the nucleus for coronavirus replication is variable, but optimum levels of progeny are obtained only in its presence. Several coronavirus proteins involved in RNA synthesis travel to the nucleus. Conversely, many nuclear proteins are transported to the cytoplasm to facilitate coronavirus RNA synthesis.

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