Interestingly, whereas nsp10 binding has no effect on nsp14 N7-MTase activity, nsp10 required for nsp16 2-0-MTase activity. These data, in conjunction with those in the preceding section, highlight the importance of nsp10 as modulator of two different activities in the coronavirus proofreading and capping machinery.
Continuous and discontinuous RNA synthesis in coronaviruses part 69
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