Continuous and discontinuous RNA synthesis in coronaviruses part 69

Interestingly, whereas nsp10 binding has no effect on nsp14 N7-MTase activity, nsp10 required for nsp16 2-0-MTase activity. These data, in conjunction with those in the preceding section, highlight the importance of nsp10 as modulator of two different activities in the coronavirus proofreading and capping machinery.

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