Continuous and discontinuous RNA synthesis in coronaviruses part 60

The nsp7-nsp8-nsp12 complex formed in vitro is able to catalyze de novo synthesis of relatively long RNAs (up to 340 nt) in a processive manner. Also interacting with nsp8 is nsp9, a small protein that binds ssRNA without sequence specificity. Dimerization of nsp9 is critical for virus replication, and its structural and functional features strongly suggest that it could be a component of the RTC catalytic core, stabilizing viral RNAs during RNA synthesis and processing.

About azaleaazelia

A nice person... :)
This entry was posted in Tak Berkategori. Bookmark the permalink.

Leave a Reply

Fill in your details below or click an icon to log in: Logo

You are commenting using your account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s