Continuous and discontinuous RNA synthesis in coronaviruses part 35

030320_coronavirus_image_from_cdc

 

During infection, RNA viruses dynamically interact with stress granules and P bodies, leading to varying stress granule phenotypes. Many virus have evolved mechanisms to antagonize the formation of stress granules, suggesting that stress granules are involved in restricting virus replication through RNA silencing.  In contrast, other RNA viruses, such as respiratory suncytial virus, induce stress granule formation and take advantage of stress granule responses as part of the infectious cycle.

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