Continuous and discontinuous RNA synthesis in coronaviruses part 2

030320_coronavirus_image_from_cdc

 

Coronavirus RNA synthesis is performed by a replication-transcription complex that includes viral and cell proteins that recognize cis-acting RNA elements  mainly located in the highly structured 5′ and 3′ untranslated regions. In addition to many viral nonstructural proteins, the presence of cell nuclear proteins, the presence of cell nuclear  proteins and the viral nucleocapsid  protein increase virus amplification efficacy.

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