Structure, function and antigenicity of the SARS-CoV-2 spike glycoprotein part 45

 

 

030320_coronavirus_image_from_cdcThe elicitation of of a heterotypic response blocking SARS-CoV-2 S-mediated entry into host cells concurs with the sequence and structural  conservation of SARS-CoV-2 S and SARS-CoV S along with their comparable glycans shields and suggests that immunity against one virus of the sarbecovirus subgenus can potentially provide protection against related viruses.

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