Structure, function and antigenicity of the SARS-CoV-2 spike glycoprotein part 28



These result suggest that S1/S2 cleavage during S biosynthesis was not necessary for S-mediated entry in the conditions of experiments. The speculation  that the detection of a polybasic cleavage site in the fusion glycoprotein of SARS-CoV-2 could putatively expand its tropism and/or enhance its transmissibillity, compared with SARS-CoV and SARSr-CoV isolates, due to the near-ubiquitous distribution of furin-like proteases.

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