Structure, function and antigenicity of the SARS-CoV-2 spike glycoprotein part 23



Sequence analysis of SARS-CoV-2 S reveals the presence of a four amino acid residue insertion at the boundary between S1 and S2 subunits compared with SARS-CoV S  and SARSr-CoV S. This results in the introduction of a furin cleavage site, a feature conserved among the 144 SARS-CoV-2 isolates sequenced to date but not in the closely related RaTG13 S.

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