Structure, function and antigenicity of the SARS-CoV-2 spike glycoprotein part 3



The SARS CoV-2 spike glycoprotein harbors a furin cleavage site at the boundary between the S1/S2 subunits, which is processed during biogenesis and sets this virus apart from SARS-CoV and SARS-related CoVs. Cryo-EM structures of the SARS-CoV-2 spike ectodomain trimer providing a blueprint for the design of vaccines and inhibitors of viral entry. SARS-CoV spike murine polyclonal antibodies potentially inhibited SARS-CoV spike mediated entry into cells, indicating that cross-neutralizing antibodies targeting conserved spike epitopes can be elicited upon vaccination.

About azaleaazelia

A nice person... :)
This entry was posted in Tak Berkategori. Bookmark the permalink.

Leave a Reply

Fill in your details below or click an icon to log in: Logo

You are commenting using your account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s