Structures and functions of Coronavirus proteins part 10

030320_coronavirus_image_from_cdc

 

S Glycoproteins

S glycoproteins are located outside the virion and give the virion the typical shape. The S protein form  homotrimers, which allow the formation of sun-like morphologies that give the name of Coronavirus. S proteins bind to virion membrane via the C-terminal transmembrane regions and they also interact with M proteins. Virions can be bound  to specific surface receptors in the plasma membrane of the host cell via the N-terminus of the S proteins.

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