Receptor Recognition Mechanism of Coronaviruses part 61

030320_coronavirus_image_from_cdc

 

Subtle structural changes in viral RBDs can lead to a complete receptor switch. For example, HCoV-NL63 and PRCV recognize two different protein receptors using structurally conserved S1-CTDs with divergent RBMs, and so do SARS-CoV and MERS-CoV. Moreover, MHV and BCoV S1-NTDs recognize a protein receptor and a sugar receptor, respectively, through subtle conformational changes in receptor-binding loops.

About azaleaazelia

A nice person... :)
This entry was posted in Tak Berkategori. Bookmark the permalink.

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Google photo

You are commenting using your Google account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s