Receptor Recognition Mechanism of Coronaviruses part 53

030320_coronavirus_image_from_cdc

 

Receptor binding by coronaviruses

How do S1-NTDs and S1-CTDs work together in the receptor recognition and evolution of coronavirus spikes? Electron microscopic studies of the SARS-CoV spike revealed that it is a clove-shaped trimer, with three individual S1 heads and trimeric S2 stalk.

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