Bat coronaviruses and human coronavirus 229E(HCoV-229E) and NL63(HCoV-NL63)
HCoV-229 was found in the 1960s and causes comparatively mild common colds worldwide. A bat coronavirus detected in Hipposideros caffer ruber in genetically related to HCoV-229E. Its RdRp fragment shared 92% nucleotide sequence identity with HCoV-229E and they were predicted to share a most recent common ancestor (MRCA) only 200 years ago.