Human coronaviruses part 27



Rs3367 showed a particularly high sequence identity to SARS-CoV in several key amino acids residue known to be important for receptor binding. Whole genome sequencing  revealed that Rs3367 and RsSHC014 shared more than 95% genome sequence identity with human and civets  SARS-CoV, which was remarkably higher than that of any other bat  SL-CoV (76 to 92%). Regarding individual genes , the amino acids  sequence identity between Rs3367 or Rs SHC014 and SARS-CoV was higher than 96% in ORF1a, 1b, 3a, 3b, E, M and N genes.

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