Preterm premature rupture of membranes, usually followed by preterm delivery, accounts for another 25% of all preterm births (range 7.1%-51.2%). This condition occurs more often in the disadvantaged population, and among Afro-American women. Infection is usually regarded as the main cause of preterm premature rupture of membranes although, in some cases, it is preceded by spontaneous preterm labour.
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