Along with bone marrow mesenchymal stem cells, adipose stem cells have received attention for cartilage regeneration. Extensive investigations on chondrogenesisfrom adipose stem cells in the last 15 years provided the basis of clinical application (Zuk et al., 2001). As with bone marrow mesenchymal stem cells, there is  a paucity of controlled  clinical investigations on regeneration of articular cartilage using adipose stem cells.