Besides cartilage defects in the knee joints, a group applied bone marrow aspirate concentration to repair of talar osteochondral lesion in 48 patients. After minimum follow-up of 24 months (mean 29 months; range, 24-35 months), the American Orthopaedic Foot and Ankle Society  score improved from 64.4 to 91.4. Histologic evaluation showed regenerated tissue and various degree of remodelling; however, none showed entirely (hyaline cartilage (Giannini et al; 2009).