Clinical use of stem cells in orthopaedics part 30

Stem cell 2

 

Daltro et al. conducted a phase I/II, non-controlled study to determine the efficacy and safety of bone marrow aspirate concentration implantation using a minimally invasive technique in 89 sickle cell disease patients with osteonecrosis of the femoral head. At the final follow-up (60 months) there was a significant improvement in clinical joint symptoms and pain relief. In addition, radiographic assessment after the bone marrow aspirate concentration implantation procedure showed disease stabilisastion (Daltro et al., 2015)

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