Clinical use of stem cells in orthopaedics part 10

Stem cell 2


To treat a large bone defect, harvesting a large portion of bone from other parts of the body inevitably creates significant morbidity at the donor site. Allografts from cadavers carry a risk of infection and disease transmission, as well as failure to incorporate into host bone if used in bulk. Bone substitute materials have limited osteogenic potential, and are not useful for complex bone reconstructions.

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