Alzheimer’s disease and stem cell therapy part 10

Stem cell 5


While late-onset alzheimers disease occurs in people aged 65 or older, familial alzheimers disease develops earlier because familial alzheimers disease is triggered by gene mutations of amyloid precursor protein  (chromosome 21), multiprotein complex comprising presenilin/PSEN 1 (chromosome 14), or PSEN 2 (chromosome 1), thereby eliciting beta-amyloid aggregation in earlier years. Of these three types, the PSEN 1 mutation has a relatively high proportion of beta-amyloid42. As beta-amyloid42 is more toxic than beta-amyloid40, familial alzheimers disease progresses more rapidly in this case, and the time of onset can come as early as 20-30 years of age.

About azaleaazelia

A nice person... :)
This entry was posted in Tak Berkategori. Bookmark the permalink.

Leave a Reply

Fill in your details below or click an icon to log in: Logo

You are commenting using your account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s