Not all stem cells are created equal part 6

Stem cell 1

 

Markers of intrinsic regenerative capacity

Other studies suggest significant variation in intrinsic regenerative capacity, which could be useful to identify likely responders versus nonresponders. In FOCUS-CCTRN (First Mononuclear Cells Injected in the United States Study Conducted by the Cardiovascular Cell Therapy Research Network), patients with chronic ischemic cardiomyopathy received transendocardial delivery of autologous bone marrow cells or placebo. Patients with improved left ventricle ejection fraction, left ventricle end-systolic volume, and VO2max at 6 months (responders) were compared with patients failing to respond in at least 1 measure (nonresponders). Irrespective of treatment, responders had higher frequencies of B-cells and CXCR4+bone marrow cells, with fewer endothelial cell colony formation units and macrophages, suggesting a bone marrow cells profile of patients with superior regenerative capacity.

Advertisements

About azaleaazelia

A nice person... :)
This entry was posted in Tak Berkategori. Bookmark the permalink.

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Google photo

You are commenting using your Google account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s