Immunological aspects of allergy and anaphylaxis part 32



Experimental Models

Animal models of ocular allergies have been developed in the past years to establish new therapeutic approaches and assess immunological mechanisms. The current animal models are based on sensitization to and subsequent challenge with small numbers of allergens such as ovalbumin (Ova), ragweed pollen, or cat epithelium. The murine model of allergic conjunctivitis represents the presently preferred species for investigating the immunological basis of the disease.

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