IMMUNOLOGY OF HIV INFECTIONS part 21

HIV AIDS 1

 

However, the problem has been whether these variants, like SHIV 89.6P, are relevant to HIV infections. For example, they exhibit an “X4” cellular tropism and are therefore easier to contain by vaccine-induced immune response than “R5” viruses such as SIV. If we could obtain SHIV strains with R5 tropism, this might be a better model to study.

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