AUTOIMMUNITY part 14

 

 

Immune 4CASE I. AUTOIMMUNE HEMOLYTIC ANEMIA (AIHA)

A. TYPE II AUTOIMMUNE REACTION

COMMENT:

AIHA can occur in a variety of circumstances, including neoplastic diseases (most often lymphomas), connective tissue diseases (such as SLE), and infections (viral, bacterial, or mycoplasma). Or it may be drug induced (classically penicillin). The initial treatment is to diagnose and treat the underlying cause or remove offending agents. If this is not possible, corticosteroid such as prednisone are often used. If patients  do not respond, then consideration  is given to the use of cytotoxic drugs (eg azathioprine or vincristine) or splenectomy.

 

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