Immunological aspects of immunodeficiency diseases part 104

Immune 3


Deficiency of components required for generating the classical partly C3-convertase may result in impairment of the process described earlier for eliminating immune complexes and “safe” disposal of apoptotic cells. This would explain the increased incidence of SLE-like disorders in patients with inherited C1q, C1r, C1s, C4, C2, C3, factor I, or factor H deficiency.

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