Immunological aspects of immunodeficiency diseases part 39

Immune 3




Patients with impaired T-cell function may develop the following:

  • Viral infections: Infections with exanthematous viruses (measles, chicken pox) can be fatal in children with T-cell deficiency. These viruses are not a problem in adults as they have residual protective antibody responses generated by primary infection or immunization. Adults with T-cell deficiency are typically affected by the reactivation of latent viruses (eg cytomegalovirus, Herpes simplex), which can produce life-threatening disseminated infections

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