Immunological aspects of immunodeficiency diseases part 8

Immune 3

 

CLINICAL MANIFESTATIONS OF ANTIBODY DEFICIENCY

KEY CONCEPTS

Patients with antibody deficiency typically develop recurrent infection with encapsulated bacteria such as Streptococcus pneumoniae and Haemophillus influenzae type B. The common sites affected are the upper and lower respiratory tracts and the middle ear. From these sites, infection can spread via the bloodstream to produce metastatic infection, for example, meningitis or bone and joint infection.

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