Basic components of the immune system part 139

Immune 1


IFN-γ is a potential activator of macrophages and is most often used in conditions in which defective macrophage function  occurs. Examples of these disorders are lepromatous leprosy, leishmaniasis and chronic granulomatous disease. IFN-γ works by increasing phagocytic bactericidal activity, but only some patients show enhanced superoxide activity, implying that  IFN-γ works by several different mechanisms.

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