Basic components of the immune system part 103

Immune 1


Complement Assays

Perhaps the most useful assays for complement are the immunochemical assays of C3 and C4. As noted, which outlines the alternative and classical modes of complement breakdown, a low C3 and C4 but normal factor B suggest that activation of the classical pathways has occured. Examples would be patients with systemic lupus erythemathosus or vasculitis. In contrast, if C3, C4, and factor B are all low, the alternative pathway is also activated via either feedback loops or simultaneous activation. This would point to a gram negative bacteremia. Normal C4 levels with low C3 and factor B levels suggests acute or  chronic infection. Acute rheumatic fever is such an example.


About azaleaazelia

A nice person... :)
This entry was posted in Tak Berkategori. Bookmark the permalink.

Leave a Reply

Fill in your details below or click an icon to log in: Logo

You are commenting using your account. Log Out /  Change )

Google photo

You are commenting using your Google account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s