Basic components of the immune system part 85

Immune 1




These reaction are those that involve antigens that react with IgE bound to tissue mast cells or basophils. Activation of the mast cell results in the release of large amounts of pharmachologically active substances. These reactions are rapid (hence immediate) and if injected into the skin  a “wheel and flare” reaction can be seen within five to ten minutes. Most antigens stimulating IgE are either inhaled or ingested. A perfect example of the inhaled antigen is ragweed pollen. The IgE production  requires helper T cells and T-cell-derived cytokines. IL-4 and IL-13 stimulate IgE production while IFN-γ is inhibiting. Many factors regulate the balance between help and suppression, including route of administration, physical nature of the substance, and the genetic background of either animals or humans. In the latter, there s a family tendency to these reactions but exact genetic factors are still ill defined.

About azaleaazelia

A nice person... :)
This entry was posted in Tak Berkategori. Bookmark the permalink.

Leave a Reply

Fill in your details below or click an icon to log in: Logo

You are commenting using your account. Log Out /  Change )

Google photo

You are commenting using your Google account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s