Basic components of the immune system part 60

Immune 1


Cytotoxic T cells also play a role in graft rejection.This was shown years ago in a mixed lymphocyte reaction in which the lymphocytes from two genetically different individuals were placed in culture. In this case, helper cells responded to a foreign MHC class II antigen, but cytotoxic T cells were able to lyse target cells carrying the MHC class I molecules of the stimulating (genetically different individual) cells.

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