Basic components of the immune system part 20

Immune 1

 

Thus, the diversity of antigen binding is achieved by the large number of V genes available and their combination with different  D and L genes to provide different antibodies. Furthermore, the inherited set of genes may be increased  by somatic mutation during multiple divisions of lymphoid cells, thereby increasing the number of antibody specifities to 10 (14), which far exceeds the number of B cells 10(10) in the body

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