HLA antibody testing part 18

HLA antibodies

 

Locus consideration

The laboratory experience that antibodies to Cw and DP antigens must be detected at much higher mean fluorescence intensity than donor-specific HLA antibody at other   loci before a positve crossmatch occurs. Other laboratories may use different mean fluorescence thresholds for identifying antibodies at different HLA loci on the basis of their own validation studies.

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