HLA system in solid organ transplantation part 31

histocompatibility testing

 

After the numerical designation, further letters are used as follows to designate other characteristics of the HLA alleles:

  • N to indicate non-coding sequence or null alleles
  • L low expression
  • S secreted, soluble but not surface expression
  • C cytoplasmic expression only
  • Q questionable expression
  • A aberrant or doubtful expression

For example, a given allele could be denoted as HLA-A*01:01:111:01A

A complete list of currently identified HLA alleles is piblished in the HLA dictionary and updated regularly.

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