HLA typing in organ transplant part 8

mhc class 1 & ii

 

In transplantation immunology, the major impact in graft loss comes from the effects of HLA-B and HLA-DR antigens.  The effect of HLA-DR mismatches are the most important in the first 6 moths after transplantation, the HLA-B effect emerges in the first 2 years, and HLA-A mismatches have a deleterious effect on long-term graft survival.

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