Human Leukocyte Antigen (HLA) part 53

hla protein 1


Atypical HLA class I deficiencies  are characterized by less severe reduction in surface expression of HLA class I molecules (approximately tenfold). It is called atypical due to  absence of clinical symptoms, and if present, it will be transient or moderate. It includes very heterogenous group due to  heterogenous molecular defects that are present  in this type. Patient with atypical HLA class I deficiency  will have a homozygous  HLA genotype and evidence of a transporter associated with antigent processing  2 deficiency. Thus transporter associated with antigen deficiency may lead to variably severe reductions in the surface levels of HLA class I molecules.


About azaleaazelia

A nice person... :)
This entry was posted in Tak Berkategori. Bookmark the permalink.

Leave a Reply

Fill in your details below or click an icon to log in: Logo

You are commenting using your account. Log Out /  Change )

Google photo

You are commenting using your Google account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s