Human Leukocyte Antigen (HLA) part 38

hla protein 1

 

In some cases, HLA genes are co-located on chromosome 6 such that they are inevitably inherited  “en bloc” and are linked as are the HLA-DRB1 and DRB3-5 genes. For example, the -DR15:01 allele is always found  with the -DRB5 gene.  In some cases, there is conserved inheritance of alleles on the same chromosome constituting a haplotype. HLA genes and their protein allotypes can sometimes  be identified on commonly recognized haplotypes.

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