Human Leukocyte Antigen (HLA) part 29

hla protein 1


The major histocompatibility complex (MHC) is a large gene complex present in all jawed vertebrates with an integral role in the immune system. The antigen-presenting molecules encoded by the MHC class I and class II genes are cell-surface glycoproteins that bind intracellular and extracellular peptides, respectively. The human MHC is located chromosome 6 and contains more than 200 genes. The MHC-encoded glycoproteins are known as human leukocyte antigen (HLA) and are specialized in presentation of short peptides to T cells  and play a key role in the body’s immune defence.

MHC name is derived from its role in graft rejection and tissue compatibility between donor-recipient pair. MHC compatibility between individuals  is responsible  for successful graft transplant. MHC is characterized by extensive polymorphism which is one hand is obstacle for finding matched pairs and in the other hand enables the immune system to recognized any invading pathogen.


About azaleaazelia

A nice person... :)
This entry was posted in Tak Berkategori. Bookmark the permalink.

Leave a Reply

Fill in your details below or click an icon to log in: Logo

You are commenting using your account. Log Out /  Change )

Google photo

You are commenting using your Google account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s