Human Leukocyte Antigen (HLA) part 7

hla protein 1


Exposure to another person’s HLA antigens may also induce alloactivation of T lymphocytes. Two general pathways of T-cell alloactivation have been recognized in transplant immunity.

The direct pathway refers to the alloreactive responses of recipient T cells to donor APC expressing incompatible HLA antigens. It provides a powerful mechanism of T-cell alloactivations.

In the indirect pathway, allogenic HLA antigens are released from donor cells, then taken up and processed (through the exogenous pathway) by recipient APC, and presented to recipient T cells as allopeptides bound to self-HLA  molecules


About azaleaazelia

A nice person... :)
This entry was posted in Tak Berkategori. Bookmark the permalink.

Leave a Reply

Fill in your details below or click an icon to log in: Logo

You are commenting using your account. Log Out /  Change )

Google photo

You are commenting using your Google account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s