Pediatric kidney transplantation part 3



Sign of chronic kidney disease and kidney failure in children

Level of kidney function is determined by the glomerular filtration rate or GFR. The GFR  is expressed as  ml/min/1.73m2. Normal kidney function is considered 90-120 ml/min/1.73m2. We estimate kidney function in children using the equation that include child’s height as well as their serum creatinine. Chronic kidney disease in children is when the kidney filtration falls below 90 ml/mim/1.73m2 for 3 or more months. Chronic kidney disease state 5 or end stage kidney disease in children is when this number falls below 15 ml/min/1.73m2

Signs and symptoms of chronic kidney disease in children can vary an can be quite subtle. The first signs of decreased kidney function may be abnormal bone health and poor growth. These effects can occur with a decrease in kidney function to 60-70% of normal. Frequently children  with decreased kidney function feel normal until their kidney function is very low at wich time some children may have fatigue, decreased appetite, nausea, the feeling of fullness when they are eating , lack of adequate weight gain, and at time decreased school performance.



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